SCHEMBL28014118

SCHEMBL28014118

Cc1c(N)ccc2c1C(C)c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.36
HTR2B P41595 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
PIK3CA P42336 1/20 0.35
GPR3 P46089 2/20 0.34
HTR2A P28223 1/20 0.34
POLB P06746 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAOA P21397 2/20 0.31
FGR P09769 1/20 0.31
PIM1 P11309 1/20 0.31
ADORA2A P29274 1/20 0.31
CSNK1A1 P48729 1/20 0.31
CSNK1D P48730 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19675665 0.81 GPR3 (0.36) HTR7HTR2BCYP3A4TSHRGPR3
SCHEMBL29285278 0.79 ALDH1A1 (0.41) HTR7HTR2BCYP3A4TSHRPIK3CA
SCHEMBL30987013 0.79 ALDH1A1 (0.41) HTR7HTR2BCYP3A4TSHRPIK3CA
SCHEMBL6292515 0.79 GPR3 (0.34) HTR7HTR2BGPR3HTR2APOLB
SCHEMBL1871454 0.79 GPR3 (0.34) HTR7HTR2BGPR3HTR2APOLB
SCHEMBL2130008 0.76 HTR7 (0.35) HTR7HTR2BGPR3POLB
SCHEMBL14119375 0.76 ALDH1A1 (0.34) HTR7HTR2BGPR3ALDH1A1MAOA
SCHEMBL626475 0.74 ADORA2A (0.37) HTR7HTR2BCYP3A4TSHRPOLB
SCHEMBL616348 0.73 PTPRC (0.39) HTR7CYP3A4ALDH1A1
SCHEMBL31338566 0.73 GPR3 (0.39) HTR7HTR2BTSHRGPR3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104718208-A Novel compound and organic electroluminescent device comprising same DOOSAN CORP 2015-06-17 CN disclosed