SCHEMBL626475

SCHEMBL626475

Cc1ccc(N)c2c1C(C)c1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.37
CSNK1A1 P48729 2/20 0.37
CSNK1D P48730 2/20 0.37
CSNK1G1 Q9HCP0 2/20 0.37
FGR P09769 1/20 0.37
PIM1 P11309 1/20 0.37
MAOA P21397 1/20 0.37
DYRK1A Q13627 1/20 0.37
HIPK2 Q9H2X6 1/20 0.37
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
MAPK1 P28482 2/20 0.34
RAB9A P51151 2/20 0.34
CYP3A4 P08684 2/20 0.34
NPC1 O15118 1/20 0.34
TSHR P16473 1/20 0.34
CASP3 P42574 1/20 0.34
HBB P68871 1/20 0.34
SENP7 Q9BQF6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014118 0.74 HTR7 (0.36) ADORA2ACSNK1A1CSNK1DCSNK1G1FGR
SCHEMBL31338566 0.72 GPR3 (0.39) ALDH1A1TSHRMEN1KMT2ANPSR1
SCHEMBL358532 0.72 GPR3 (0.39) ALDH1A1TSHRMEN1KMT2ANPSR1
SCHEMBL29285278 0.71 ALDH1A1 (0.41) ADORA2AALDH1A1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL30987013 0.71 ALDH1A1 (0.41) ADORA2AALDH1A1SMN1; SMN2L3MBTL1MAPK1
Methyl Alcohol SCHEMBL14815699 0.69 ALDH1A1 (0.38) ALDH1A1MEN1POLBKMT2AHTR2C
SCHEMBL19675665 0.69 GPR3 (0.36) ALDH1A1SMN1; SMN2L3MBTL1MAPK1RAB9A
SCHEMBL8388473 0.67 GPR3 (0.33) DRD2DRD4
SCHEMBL7607095 0.67 HTR2A (0.42) ALDH1A1SMN1; SMN2L3MBTL1MAPK1RAB9A
Hydrochloric Acid SCHEMBL7604175 0.67 NPC1 (0.32) ALDH1A1SMN1; SMN2L3MBTL1MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114784212-A Organic electroluminescent device and electronic apparatus including the same 陕西莱特光电材料股份有限公司 2022-07-22 CN disclosed
EP-2603540-B1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2021-04-21 EP disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
EP-2603540-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS Merck Patent GmbH (DE) 2013-06-19 EP disclosed
US-20130137818-A1 POLYMERS HAVING CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2013-05-30 US disclosed
WO-2012019724-A1 POLYMERS WITH CARBAZOLE STRUCTURAL UNITS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed