Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015695 | 0.84 | NPC1 (0.35) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28015173 | 0.83 | HSD11B1 (0.38) | HSD11B1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL28015709 | 0.83 | ALOX5 (0.40) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28015710 | 0.81 | IKBKE (0.39) | KMT2AADORA3HSD11B1MGAMGAA | |
| SCHEMBL28015664 | 0.79 | HSD11B1 (0.40) | KMT2AHSD11B1MGAMGAASI | |
| SCHEMBL2921081 | 0.78 | KMT2A (0.40) | KMT2AADORA3MGAMGAASI | |
| SCHEMBL28015735 | 0.76 | RAB9A (0.37) | KMT2AHSD11B1MGAMGAASI | |
| SCHEMBL28015748 | 0.76 | ADORA3 (0.49) | KMT2AADORA3MGAMGAASI | |
| SCHEMBL2920964 | 0.73 | PDE4B (0.36) | KMT2AADORA3MGAMGAASI | |
| SCHEMBL13846452 | 0.73 | PDE4A (0.36) | KMT2AADORA3MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |