Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015709 | 0.84 | ALOX5 (0.40) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28015124 | 0.83 | KMT2A (0.39) | HSD11B1RAB9ANPC1PTGS1PTGS2 | |
| SCHEMBL28015664 | 0.81 | HSD11B1 (0.40) | HSD11B1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28015158 | 0.79 | HSD11B1 (0.38) | HSD11B1RAB9ANPC1PTGDR2CASP3 | |
| SCHEMBL28015735 | 0.78 | RAB9A (0.37) | HSD11B1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28015695 | 0.74 | NPC1 (0.35) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL28015190 | 0.73 | NPC1 (0.46) | HSD11B1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL28015197 | 0.73 | CASP3 (0.46) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL12210686 | 0.73 | HSD11B1 (0.38) | HSD11B1RAB9ANPC1PTGS2SMN1; SMN2 | |
| SCHEMBL28015742 | 0.72 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |