Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015173 | 0.84 | HSD11B1 (0.38) | RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28015124 | 0.83 | KMT2A (0.39) | RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28015695 | 0.83 | NPC1 (0.35) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28015735 | 0.80 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2MAPTHTT | |
| SCHEMBL28015742 | 0.80 | ALDH1A1 (0.38) | RAB9ANPC1SMN1; SMN2MAPTHTT | |
| SCHEMBL900791 | 0.78 | ALOX5 (0.43) | ALOX5RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28015190 | 0.75 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2MAPTHTT | |
| SCHEMBL18137264 | 0.75 | HPRT1 (0.43) | ALOX5RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL906904 | 0.74 | TLR8 (0.42) | ALOX5RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL28015664 | 0.74 | HSD11B1 (0.40) | RAB9ANPC1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |