Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIK1 | P57059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543195 | 0.81 | ALK (0.37) | ABCB1NPY5RMAPTKDM4EALDH1A1 | |
| SCHEMBL16430537 | 0.72 | L3MBTL1 (0.50) | NPY5RMCHR1MAPTALDH1A1HTT | |
| SCHEMBL5542974 | 0.72 | MAPT (0.39) | ABCB1NPY5RMCHR1MAPTKDM4E | |
| SCHEMBL8726329 | 0.69 | L3MBTL3 (0.42) | NPY5RMCHR1MAPTKDM4EALDH1A1 | |
| SCHEMBL21847022 | 0.68 | LGMN (0.42) | NPY5RMAPTALDH1A1PLK1 | |
| SCHEMBL16432042 | 0.67 | NPY5R (0.43) | NPY5RMAPTALDH1A1MEN1LMNA | |
| SCHEMBL517751 | 0.67 | ALDH1A1 (0.62) | MAPTKDM4EALDH1A1HTTGFER | |
| SCHEMBL517750 | 0.67 | ALDH1A1 (0.62) | MAPTKDM4EALDH1A1HTTGFER | |
| SCHEMBL16430647 | 0.65 | FAAH (0.46) | NPY5RMCHR1MAPTALDH1A1GFER | |
| SCHEMBL94337 | 0.65 | MCHR1 (0.50) | MCHR1MAPTALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |