Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016834 | 0.88 | HSD11B1 (0.52) | MGLLCYP11B1CYP11B2NPC1SMN1; SMN2 | |
| SCHEMBL20561090 | 0.88 | SLC6A3 (0.47) | MGLLCYP11B1CYP11B2MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28016225 | 0.87 | SLC6A3 (0.46) | MGLLCYP11B1CYP11B2MAPTSMN1; SMN2 | |
| SCHEMBL20561089 | 0.86 | KCNK3 (0.49) | MGLLCYP11B1CYP11B2PNLIPHSD11B1 | |
| Chlorobenzene SCHEMBL28024378 | 0.82 | CYP11B1 (0.49) | MGLLCYP11B1CYP11B2PNLIPANO1 | |
| SCHEMBL28024425 | 0.77 | KCNK3 (0.46) | MGLLCYP11B1CYP11B2PNLIPANO1 | |
| SCHEMBL6852259 | 0.77 | HPGD (0.60) | MGLLNPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL23014496 | 0.75 | PNLIP (0.51) | MGLLCYP11B1CYP11B2PNLIPANO1 | |
| SCHEMBL29111430 | 0.74 | UTS2R (0.48) | MGLLNPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL247591 | 0.74 | CES2 (0.65) | NPC1MAPTSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104800228-A | Applications of O-benzoyl-(4-trifluoromethyl) salicylamide compound in preparing drugs used for treating intestinal cancer | HANGZHOU MINSHENG PHARM GROUP | 2015-07-29 | — | — | CN | disclosed |
| CN-104800227-A | Applications of O-benzoyl-(4-trifluoromethyl) salicylamide compound in preparing drugs used for treating lung cancer | HANGZHOU MINSHENG PHARM GROUP | 2015-07-29 | — | — | CN | disclosed |