SCHEMBL28021005

SCHEMBL28021005

COC(=O)C(N=N)(N=N)P(=O)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.31
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27995412 0.81
SCHEMBL9066294 0.69 DGAT1 (0.39) L3MBTL1DGAT1
SCHEMBL27352017 0.67 DGAT1 (0.37) DGAT1
SCHEMBL6120239 0.67 L3MBTL1 (0.34) L3MBTL1DGAT1
SCHEMBL9770200 0.67 KCNN4 (0.34) L3MBTL1DGAT1
SCHEMBL1874420 0.62 L3MBTL1 (0.31) L3MBTL1DGAT1
SCHEMBL21562601 0.60 DGAT1 (0.32) DGAT1
SCHEMBL17213480 0.60 DGAT1 (0.35) DGAT1
SCHEMBL160191 0.59
SCHEMBL3178598 0.59 L3MBTL1 (0.35) L3MBTL1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102762574-B Benzoxapi 3K inhibitor compounds and methods of use HOFFMAN-LA ROCHE LTD. (CH) 2015-12-02 CN disclosed
CN-104987345-A BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE HOFFMANN LA ROCHE 2015-10-21 CN disclosed