Anthrone

Anthrone

SCHEMBL28021908

O=C1c2ccccc2Cc2ccccc21.O=CC(O)C(O)C(O)C(O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.50
CES1 P23141 2/20 0.40
BCHE P06276 1/20 0.40
ALDH1A1 P00352 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
MIF P14174 5/20 0.37
MAOB P27338 1/20 0.37
CYP19A1 P11511 2/20 0.37
TNF P01375 2/20 0.37
KDM4E B2RXH2 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
STK17B O94768 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TYR P14679 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthrone SCHEMBL28448038 0.96 MAOA (0.46) MAOACES1BCHEALDH1A1CYP1A2
Anthrone SCHEMBL28448041 0.96 MAOA (0.46) MAOACES1BCHEALDH1A1CYP1A2
Anthraquinone SCHEMBL28146014 0.90 MEN1 (0.41) MAOACES1BCHEALDH1A1CYP1A2
Naphthoquinone SCHEMBL27790071 0.80 CDC25B (0.44) MAOACES1BCHEALDH1A1CYP1A2
Demannose SCHEMBL27878620 0.77 L3MBTL1 (0.41) CYP1A2CYP2C19KDM4EMEN1KMT2A
Demannose SCHEMBL27784462 0.75 LMNA (0.50) CYP2C19KDM4E
Anthracene SCHEMBL27775840 0.74 L3MBTL1 (0.38) ALDH1A1CYP1A2MEN1KMT2AMAPT
Demannose SCHEMBL27735211 0.74 TDP1 (0.38) KDM4EMAPT
Demannose SCHEMBL3515070 0.74 TDP1 (0.38) KDM4EMAPT
Demannose SCHEMBL28198426 0.73 LMNA (0.48) CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116327880-A Nebulizable anti-fatigue pharmaceutical composition 深圳雾芯科技有限公司 2023-06-27 CN disclosed
CN-107468681-B The drug and pharmaceutical composition of prevention or treatment prediabetes 大连理工大学 2019-11-19 CN disclosed
CN-109988139-A A kind of chromocor derivative and its medical usage 天津医科大学 2019-07-09 CN disclosed
CN-107468681-A Prevention or the medicine and pharmaceutical composition for the treatment of prediabetes 大连理工大学 2017-12-15 CN disclosed
CN-104853733-A Pearlescent hair care compositions OTC GMBH 2015-08-19 CN disclosed