Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624564 | 0.81 | ALOX15 (0.41) | ALOX15ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28025288 | 0.79 | ALOX15 (0.38) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL20449061 | 0.78 | TAAR1 (0.41) | ALOX15ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11123121 | 0.78 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL5584092 | 0.77 | GPR84 (0.49) | ALOX15ALDH1A1MAPTNPSR1 | |
| SCHEMBL14036889 | 0.75 | KDM4E (0.44) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL14094653 | 0.75 | RIPK1 (0.42) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL18901018 | 0.74 | DPP4 (0.44) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL28861332 | 0.74 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL28583866 | 0.74 | ALOX15 (0.43) | ALOX15ALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102292321-B | Pyrazolyl-substituted carbonic acid derivatives as modulators of the prostacyclin (PGI2) receptor for the treatment of receptor-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2015-08-12 | — | — | CN | disclosed |