Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303681 | 0.86 | LPL (0.34) | MAPTNPC1RAB9A | |
| SCHEMBL28025953 | 0.83 | HSD11B1 (0.44) | TP53SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28025444 | 0.82 | TAAR1 (0.48) | TP53SMN1; SMN2NPC1ALDH1A1KDM4E | |
| SCHEMBL28025990 | 0.81 | BCL2 (0.40) | TP53MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28515419 | 0.81 | NPC1 (0.39) | TP53PTAFRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL5076754 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPK1CYP2A6TDP1 | |
| SCHEMBL28303649 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPK1CYP2A6 | |
| SCHEMBL28025966 | 0.76 | PTGS2 (0.38) | PTAFRRPS6KA2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL28025982 | 0.76 | CYP1A2 (0.43) | TP53PTAFRMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28219798 | 0.75 | PTPN1 (0.50) | TP53PTAFRMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | claimed |
| CN-108137729-B | Catalysts for forming multimodal polymers | 埃克森美孚化学专利公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-104822697-A | Bridged metallocene compounds, catalyst systems and polymerization processes using the same | EXXONMOBIL CHEM PATENTS INC | 2015-08-05 | — | — | CN | disclosed |