SCHEMBL28025520

SCHEMBL28025520

Fc1ccc(F)c(C2=C[CH]c3ccccc32)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
NFE2L2 Q16236 3/20 0.34
GPR3 P46089 1/20 0.34
PDK2 Q15119 2/20 0.33
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
PPIA P62937 1/20 0.30
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28515923 0.86 GPR3 (0.38) PTPN1L3MBTL1CASP3SENP8SENP7
SCHEMBL28025420 0.83 ALDH1A1 (0.33) PTPN1L3MBTL1SMN1; SMN2MEN1NPC1
SCHEMBL28025425 0.81 GPR3 (0.36) PTPN1GPR3
SCHEMBL28025957 0.81 PTPN1 (0.31) PTPN1
SCHEMBL28025446 0.76 TTR (0.33)
SCHEMBL28025528 0.76 CTSL (0.37)
SCHEMBL28025966 0.76 PTGS2 (0.38) CASP3SENP8SENP7SENP6PDK2
SCHEMBL28025935 0.75 GPR3 (0.31) GPR3
SCHEMBL28025419 0.75 TAAR1 (0.39) PDK2SMN1; SMN2LMNAHPGD
SCHEMBL28025517 0.74 CNR1 (0.33) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed