SCHEMBL28025939

SCHEMBL28025939

Cc1c(C)c(C)c2c(c1C)[CH]C=C2c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 2/20 0.33
CHEK1 O14757 1/20 0.33
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025941 0.76 BRD4 (0.32) AKT2KMT2AALDH1A1
SCHEMBL28303645 0.74 BRD4 (0.31) AKT2KMT2AALDH1A1
SCHEMBL8618279 0.70 LMNA (0.48) AKT2CHEK1KMT2AALDH1A1
SCHEMBL6294085 0.70 LMNA (0.48) AKT2CHEK1KMT2AALDH1A1
SCHEMBL9701681 0.68 LMNA (0.46) AKT2CHEK1KMT2AALDH1A1
SCHEMBL9701635 0.67 LMNA (0.50) AKT2CHEK1KMT2AALDH1A1
SCHEMBL28025933 0.67 FABP4 (0.35) KMT2AALDH1A1
SCHEMBL9643717 0.66 ALDH1A1 (0.39) AKT2CHEK1KMT2AALDH1A1
SCHEMBL27619559 0.65 LMNA (0.48) AKT2CHEK1KMT2AALDH1A1
SCHEMBL28025944 0.64 PDE4B (0.35) KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed