SCHEMBL28025967

SCHEMBL28025967

COc1cc(OC)cc(C2=C[CH]c3ccccc32)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 5/20 0.51
ABCB1 P08183 5/20 0.51
BCR P11274 5/20 0.51
CYP1A1 P04798 3/20 0.44
CYP1B1 Q16678 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2E1 P05181 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C8 P10632 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2A6 P11509 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP4B1 P13584 2/20 0.44
CYP2B6 P20813 2/20 0.44
CYP3A5 P20815 2/20 0.44
CYP2A7 P20853 2/20 0.44
CYP3A7 P24462 2/20 0.44
CYP2F1 P24903 2/20 0.44
CYP2C18 P33260 2/20 0.44
CYP2C19 P33261 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025547 0.87 DYRK1A (0.44) ABL1ABCB1BCRCYP1A1CYP1B1
SCHEMBL28219798 0.84 PTPN1 (0.50) ABL1ABCB1BCRKMT2AMEN1
SCHEMBL28025513 0.80 ALDH1A1 (0.41) ABL1ABCB1BCRCYP1A1CYP1B1
SCHEMBL28025423 0.77 BRD9 (0.34) KMT2AMEN1TP53TSHRMAPT
SCHEMBL28302278 0.75 BRD9 (0.33) TP53TSHRMAPT
SCHEMBL28025947 0.75 ACHE (0.35) CYP1A2CYP3A4CYP2C19KMT2AALDH1A1
SCHEMBL28219408 0.74 ALDH1A1 (0.36) CYP2A6KMT2AALDH1A1MEN1SMN1; SMN2
SCHEMBL5076754 0.73 ALDH1A1 (0.41) CYP2A6ALDH1A1HPGDTDP1PTPN1
SCHEMBL28025517 0.73 CNR1 (0.33) CYP1A2CYP2A6TDP1
SCHEMBL28025956 0.73 PTGS2 (0.49) KMT2AALDH1A1MEN1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed