Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026887 | 0.86 | KMT2A (0.40) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28027514 | 0.86 | CUL4A (0.54) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28026889 | 0.86 | CUL4A (0.54) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28026888 | 0.85 | KMT2A (0.43) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28026892 | 0.82 | CUL4A (0.48) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28026890 | 0.81 | EEF2K (0.56) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28027509 | 0.79 | CUL4A (0.55) | CUL4AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28027511 | 0.79 | ALDH1A1 (0.58) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28027503 | 0.78 | CUL4A (0.59) | CUL4A | |
| SCHEMBL28027554 | 0.75 | MAPT (0.61) | CUL4AALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968323-A | Inhibitors of CRL4 ubiquitin ligase and uses thereof | UNIV CORNELL | 2015-10-07 | — | — | CN | claimed |
| CN-104968323-A | Inhibitors of CRL4 ubiquitin ligase and uses thereof | UNIV CORNELL | 2015-10-07 | — | — | CN | disclosed |