Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288285 | 0.93 | TSHR (0.44) | CACNA2D1CACNB2CACNA1CTSHRHSD17B2 | |
| SCHEMBL17845069 | 0.90 | APP (0.48) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL2519799 | 0.86 | TSHR (0.52) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL2801832 | 0.86 | TSHR (0.52) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL8681264 | 0.83 | CYP1A1 (0.44) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL20865650 | 0.82 | ACHE (0.45) | HSD17B2LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4649365 | 0.82 | APP (0.43) | APPHSD17B2IDO1LMNAALDH1A1 | |
| SCHEMBL9669350 | 0.81 | HTR2A (0.40) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL2683928 | 0.81 | CACNA2D1 (0.40) | CACNA2D1CACNB2CACNA1CTSHRAPP | |
| SCHEMBL2686081 | 0.81 | VCP (0.46) | CACNA2D1CACNB2CACNA1CTSHRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461501-A | Green method for high-selectivity synthesis of chalcone compounds | 温州大学 | 2021-10-01 | — | — | CN | disclosed |
| US-7763734-B2 | Synthesis, structure and use of bisoxazolidines for asymmetric catalysis and synthesis | GEORGETOWN UNIVERSITY (US) | 2010-07-27 | — | — | US | disclosed |
| US-7763734-B2 | Synthesis, structure and use of bisoxazolidines for asymmetric catalysis and synthesis | GEORGETOWN UNIVERSITY (US) | 2010-07-27 | — | — | US | disclosed |
| EP-2066651-A1 | 6-(BIPHENYL-ESTER)-3H-NAPHTHO[2, 1-B]PYRANS AS PHOTOCHROMIC DICHROIC DYES AND OPTICAL ARTICLE CONTAINING THEM | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028930-A1 | 6-(BIPHENYL-ESTER)-3H-NAPHTHO[2, 1-B]PYRANS AS PHOTOCHROMIC DICHROIC DYES AND OPTICAL ARTICLE CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2008-03-13 | — | — | WO | disclosed |
| WO-2007140058-A1 | PHOTOCHROMIC MATERIALS COMPRISING METALLOCENYL GROUPS | TRANSITIONS OPTICAL, INC. (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | GEORGETOWN UNIVERSITY | 2007-11-15 | — | — | US | disclosed |
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | GEORGETOWN UNIVERSITY | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265255-A1 | SYNTHESIS, STRUCTURE AND USE OF BISOXAZOLIDINES FOR ASYMMETRIC CATALYSIS AND SYNTHESIS | ADH5, ADH1C, ADH1A | CACNA2D1 2691/4885CACNB2 3433/4885CACNA1C 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.