Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800568 | 0.83 | KDM4E (0.52) | TDP1HSD17B10NPSR1POLBCRHBP | |
| SCHEMBL11671106 | 0.76 | TP53 (0.54) | ESR1TDP1TP53HSD17B10NPSR1 | |
| SCHEMBL803612 | 0.75 | GAA (0.48) | HSD17B10NPSR1POLBCRHBPCRHR2 | |
| SCHEMBL172750 | 0.74 | TDP1 (0.52) | ESR1TDP1TP53HSD17B10NPSR1 | |
| SCHEMBL25969195 | 0.72 | GAA (0.47) | ALDH1A1ALOX15MAPTCYP1A2CYP3A4 | |
| SCHEMBL10292556 | 0.72 | ALDH1A1 (0.45) | ESR1HSD17B10NPSR1POLBESR2 | |
| SCHEMBL133847 | 0.72 | ALDH1A1 (0.48) | TDP1HSD17B10NPSR1POLBKDM4E | |
| SCHEMBL10398568 | 0.72 | CRHBP (0.65) | HSD17B10NPSR1POLBCRHBPCRHR2 | |
| SCHEMBL25969111 | 0.71 | CYP1A2 (0.43) | ESR1TDP1HSD17B10NPSR1POLB | |
| SCHEMBL1290656 | 0.71 | ESR1 (0.44) | ESR1TDP1TP53HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348132-A | 2-amino-4-acetamino anisole synthesis process | SHANGHAI HONGYUAN CHEMICAL SUPPLY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| CN-104910038-A | 3-Amino-4-methoxy acetanilide (II) preparation method | HANGZHOU YUTIAN TECHNOLOGY CO LTD | 2015-09-16 | — | — | CN | disclosed |
| CN-104788334-A | Synthesis process of 2-amino-4-acetamino anisole | SHANGHAI ZONGXING CHEMICAL TECHNOLOGY CO LTD | 2015-07-22 | — | — | CN | disclosed |