Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185396 | 0.84 | CASP6 (0.51) | HCAR3TSHRCASP6 | |
| SCHEMBL11765445 | 0.82 | LMNA (0.57) | HCAR3THRATHRBMAPTHSD17B3 | |
| SCHEMBL1612238 | 0.81 | THRA (0.51) | HCAR3THRATHRBHSD17B3 | |
| SCHEMBL19411243 | 0.80 | HCAR3 (0.55) | HCAR3THRATHRBGAAMAPT | |
| SCHEMBL9075699 | 0.80 | THRA (0.51) | HCAR3THRATHRBHSD17B3 | |
| SCHEMBL12979570 | 0.79 | THRA (0.47) | HCAR3THRATHRBGAAMAPT | |
| SCHEMBL21839460 | 0.79 | HTT (0.60) | MAPTHSD17B3 | |
| SCHEMBL145092 | 0.77 | CASP6 (0.72) | HCAR3TSHRCASP6 | |
| SCHEMBL30810715 | 0.77 | CASP6 (0.72) | HCAR3TSHRCASP6 | |
| SCHEMBL842661 | 0.77 | CASP6 (0.72) | HCAR3TSHRCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105016939-A | Preparation methods of nitrile and corresponding amine | SINOPEC YANGZI PETROCHEMICAL | 2015-11-04 | — | — | CN | claimed |
| CN-105016940-A | Process for the manufacture of nitriles and their corresponding amines | SINOPEC YANGZI PETROCHEMICAL | 2015-11-04 | — | — | CN | claimed |
| CN-105001032-A | Process for the manufacture of nitriles and their corresponding amines | SINOPEC YANGZI PETROCHEMICAL | 2015-10-28 | — | — | CN | claimed |
| CN-105016939-A | Preparation methods of nitrile and corresponding amine | SINOPEC YANGZI PETROCHEMICAL | 2015-11-04 | — | — | CN | disclosed |
| CN-105016940-A | Process for the manufacture of nitriles and their corresponding amines | SINOPEC YANGZI PETROCHEMICAL | 2015-11-04 | — | — | CN | disclosed |
| CN-105001032-A | Process for the manufacture of nitriles and their corresponding amines | SINOPEC YANGZI PETROCHEMICAL | 2015-10-28 | — | — | CN | disclosed |