SCHEMBL9075699

SCHEMBL9075699

CCCCCCCc1ccc(C(=O)CCCCC(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
ALDH1A1 P00352 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HCAR3 P49019 2/20 0.46
HSD17B3 P37058 6/20 0.46
PDK1 Q15118 1/20 0.45
SCD O00767 1/20 0.43
PPARG P37231 3/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7575190 0.84 HCAR3 (0.62) HCAR3PDK1
SCHEMBL9779790 0.84 HCAR3 (0.62) HCAR3PDK1
SCHEMBL8215974 0.83 HCAR3 (0.64) HCAR3PDK1
SCHEMBL9075580 0.81 HSD17B3 (0.49) ALDH1A1TDP1HSD17B3SCDPPARG
SCHEMBL28029786 0.80 HCAR3 (0.53) THRATHRBHCAR3HSD17B3
SCHEMBL11748103 0.79 PDK1 (0.55) THRATHRBALDH1A1TDP1HCAR3
SCHEMBL1612238 0.79 THRA (0.51) THRATHRBALDH1A1HCAR3HSD17B3
SCHEMBL27487118 0.79 HCAR3 (0.63) ALDH1A1TDP1HCAR3PDK1
SCHEMBL11602247 0.79 VCAM1 (0.53) THRATHRBALDH1A1TDP1HCAR3
SCHEMBL11765445 0.78 LMNA (0.57) THRATHRBALDH1A1TDP1HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5504244-A 3-(4-N-PENTYLPHENYLACYL)BENZOIC ACID OR SALT OR ESTER BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1996-04-02 US disclosed