Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432646 | 0.80 | PTPN11 (0.42) | LMNAMAPTMEN1KMT2ATSHR | |
| SCHEMBL28029942 | 0.80 | KDM4E (0.47) | KDM4EHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL27890273 | 0.76 | ALDH1A1 (0.50) | KDM4EHPGDALDH1A1MAPTPOLB | |
| SCHEMBL28060057 | 0.73 | TSHR (0.60) | LMNAHSD17B10POLBMEN1MAPK1 | |
| SCHEMBL28742781 | 0.70 | P2RX7 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10929848 | 0.70 | GAA (0.47) | ALDH1A1MAPTPOLBCYP3A4GAA | |
| SCHEMBL11491934 | 0.70 | TSHR (0.58) | LMNAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL21667494 | 0.69 | HPGD (0.46) | LMNAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL6394052 | 0.68 | LMNA (0.39) | LMNAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL27708885 | 0.68 | PTGS2 (0.44) | KDM4EMAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829546-A | Double-triazole substituted ethoxy benzene compound and preparation method and application thereof | UNIV TIANJIN NORMAL | 2015-08-12 | — | — | CN | disclosed |