Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.52 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030312 | 0.95 | ALPL (0.51) | MMEALPLCA12PPARGPPARA | |
| SCHEMBL28030907 | 0.88 | NR1H4 (0.58) | MMEALPLCA12CYP1A2PPARG | |
| SCHEMBL28030909 | 0.86 | MAPT (0.55) | MMEALPLCA12CYP1A2MAPT | |
| SCHEMBL28030339 | 0.81 | NR1H4 (0.58) | MMECYP1A2PPARGPPARAMAPT | |
| SCHEMBL28030908 | 0.79 | CPA1 (0.46) | MMECYP1A2MAPTPTPN1 | |
| SCHEMBL27963122 | 0.78 | MME (0.42) | MMEALPLCA12PPARGPPARA | |
| SCHEMBL4663230 | 0.72 | CYP1A2 (0.65) | CYP1A2PPARGPPARA | |
| SCHEMBL27963121 | 0.71 | MAPT (0.42) | MMEALPLCA12MAPTTP53 | |
| SCHEMBL10889952 | 0.70 | MAPT (0.48) | ALPLCA12MAPTTP53DRD2 | |
| SCHEMBL4664822 | 0.70 | CYP1A2 (1.00) | MMECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-B | 1-aryl-3-aryl-1H-pyrazoles-5-first hydroximic acid derivative and application thereof | SHANDONG UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |