Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030908 | 0.90 | CPA1 (0.46) | MAPTMEN1KMT2ANPC1POLB | |
| SCHEMBL28030312 | 0.90 | ALPL (0.51) | MAPTMMECA12ALPLTP53 | |
| SCHEMBL28030313 | 0.86 | MME (0.52) | MAPTMMECA12ALPLTP53 | |
| SCHEMBL28030907 | 0.83 | NR1H4 (0.58) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL27963156 | 0.80 | MAPT (0.53) | MAPTMEN1KMT2ANPC1POLB | |
| SCHEMBL10436410 | 0.75 | CPA1 (0.57) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL28030339 | 0.73 | NR1H4 (0.58) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9976033 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ANPC1POLB | |
| SCHEMBL9048488 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ANPC1POLB | |
| SCHEMBL29110788 | 0.71 | MAPT (0.51) | MAPTMEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-B | 1-aryl-3-aryl-1H-pyrazoles-5-first hydroximic acid derivative and application thereof | SHANDONG UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |