Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030312 | 0.92 | ALPL (0.51) | NR1H4MMEALPLCA12MAPT | |
| SCHEMBL28030339 | 0.90 | NR1H4 (0.58) | NR1H4MMEMPLMAPTPPARG | |
| SCHEMBL28030313 | 0.88 | MME (0.52) | NR1H4MMEALPLCA12MAPT | |
| SCHEMBL28030909 | 0.83 | MAPT (0.55) | MMEALPLCA12MAPTTP53 | |
| SCHEMBL28030908 | 0.72 | CPA1 (0.46) | MMEMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL5801002 | 0.71 | PPARG (0.57) | MMEMAPTPPARGEPHX2TP53 | |
| SCHEMBL4663230 | 0.71 | CYP1A2 (0.65) | PPARGEPHX2PPARAKMT2ACYP1A2 | |
| SCHEMBL27963121 | 0.69 | MAPT (0.42) | NR1H4MMEALPLCA12MAPT | |
| SCHEMBL7713441 | 0.68 | PPARG (0.71) | PPARGEPHX2PPARAMEN1KMT2A | |
| SCHEMBL7713444 | 0.68 | PPARG (0.71) | PPARGEPHX2PPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-B | 1-aryl-3-aryl-1H-pyrazoles-5-first hydroximic acid derivative and application thereof | SHANDONG UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |