Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
| ▸ | MPL | P40238 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030907 | 0.90 | NR1H4 (0.58) | NR1H4MPLMMEMEN1KMT2A | |
| SCHEMBL28030908 | 0.82 | CPA1 (0.46) | MMEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28030313 | 0.81 | MME (0.52) | NR1H4MMECYP1A2MAPTPTPN1 | |
| SCHEMBL28030312 | 0.81 | ALPL (0.51) | NR1H4MMEMAPTPTPN1TP53 | |
| SCHEMBL5801002 | 0.74 | PPARG (0.57) | MMEALDH1A1CYP1A2MAPTTP53 | |
| SCHEMBL28030909 | 0.73 | MAPT (0.55) | MMEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12089072 | 0.71 | L3MBTL1 (0.58) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL15622965 | 0.69 | NR1H4 (0.72) | NR1H4RAB9ALMNACYP1A2MAPT | |
| SCHEMBL28046606 | 0.68 | TP53 (0.57) | NR1H4MMERAB9ALMNACYP11B1 | |
| SCHEMBL14144765 | 0.67 | ALPL (0.69) | NR1H4MEN1KMT2ANPC1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103787976-B | 1-aryl-3-aryl-1H-pyrazoles-5-first hydroximic acid derivative and application thereof | SHANDONG UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |