Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449628 | 0.88 | LMNA (0.42) | ALDH1A1MAPK1CTSKMAPTTDP1 | |
| SCHEMBL8161660 | 0.81 | CTSK (0.41) | CTSKTSHRSMN1; SMN2CNR2 | |
| SCHEMBL29159429 | 0.78 | LMNA (0.44) | TDP1L3MBTL1 | |
| SCHEMBL8171846 | 0.77 | SLC6A2 (0.41) | ALDH1A1CTSKTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL27799790 | 0.77 | TDP1 (0.37) | ALDH1A1MAPK1MAPTTSHRTDP1 | |
| SCHEMBL28032633 | 0.76 | SLC6A3 (0.45) | ALDH1A1TSHRSMN1; SMN2SLC6A4SLC6A3 | |
| SCHEMBL16956351 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPK1MAPTTDP1PSEN1 | |
| SCHEMBL8166174 | 0.75 | CYP1A2 (0.42) | ALDH1A1CTSKTSHRSMN1; SMN2TDP1 | |
| SCHEMBL8170715 | 0.75 | OPRM1 (0.45) | ALDH1A1 | |
| SCHEMBL3914173 | 0.75 | CES2 (0.36) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918942-A | Pyrimidone derivatives and their use for treating, ameliorating or preventing viral diseases | SAVIRA PHARMACEUTICALS GMBH | 2015-09-16 | — | — | CN | disclosed |