Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752913 | 0.86 | SLC6A9 (0.40) | SLC6A9NR1H2CHRM4NR1H3CTSB | |
| SCHEMBL3503419 | 0.83 | SIRT6 (0.57) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL28036150 | 0.81 | HTR1A (0.48) | LMNAHTTSMN1; SMN2POLBGAA | |
| SCHEMBL2442056 | 0.79 | SLC6A9 (0.36) | SLC6A9NR1H2CHRM4NR1H3CTSB | |
| SCHEMBL17310201 | 0.79 | SMN1; SMN2 (0.51) | LMNAHTTSMN1; SMN2ALKCCR1 | |
| SCHEMBL11963285 | 0.79 | NR1H2 (0.44) | SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL26096595 | 0.79 | HTR1D (0.37) | LMNAHTTSMN1; SMN2TRPC6POLB | |
| SCHEMBL26094770 | 0.78 | LMNA (0.34) | LMNAHTTSMN1; SMN2CHRM4TRPC6 | |
| SCHEMBL29252729 | 0.77 | AGTR2 (0.48) | NR1H2CHRM4NR1H3CTSBCTSS | |
| SCHEMBL2760636 | 0.77 | DRD2 (0.51) | LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-A | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2015-10-07 | — | — | CN | disclosed |