Phenol

Phenol

SCHEMBL28036694

O=C(O)CCCl.Oc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA9 Q16790 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA14 Q9ULX7 1/20 0.50
KEAP1 Q14145 1/20 0.46
NR4A2 P43354 1/20 0.45
MAPK1 P28482 2/20 0.43
FFAR1 O14842 2/20 0.43
HDAC3 O15379 1/20 0.43
ADRA1A P35348 1/20 0.43
HDAC4 P56524 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HDAC1 Q13547 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL6388337 0.85 CA2 (0.61) CA2CA12CA1GLACA3
Succinic Acid SCHEMBL374785 0.85 CA2 (0.61) CA2CA12CA1GLACA3
Phenol SCHEMBL23276813 0.83 CA2 (0.58) CA2CA12CA1GLACA3
Phenol SCHEMBL20770751 0.83 CA2 (0.46) CA2CA12CA1GLACA3
R-Chloropropionate SCHEMBL10922210 0.83 LMNA (0.50) TDP1KEAP1NR4A2MAPK1FFAR1
Phenol SCHEMBL2369589 0.82 HDAC3 (0.59) CA2CA12CA1GLACA3
Glutarate SCHEMBL379351 0.81 HDAC3 (0.58) CA2CA12CA1GLACA3
Adipic Acid SCHEMBL523364 0.81 HDAC3 (0.59) CA2CA12CA1GLACA3
Glutarate SCHEMBL28110215 0.81 HDAC3 (0.58) CA2CA12CA1GLACA3
Fluorobenzene SCHEMBL5765024 0.80 KEAP1 (0.45) KEAP1NR4A2MAPK1FFAR1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017146-A Synthetic method for 3,4-dihydro-7-hydroxy-2(1H)-quinolinone ANHUI WANBANG MEDICAL TECHNOLOGY CO LTD 2015-11-04 CN claimed
CN-105017146-A Synthetic method for 3,4-dihydro-7-hydroxy-2(1H)-quinolinone ANHUI WANBANG MEDICAL TECHNOLOGY CO LTD 2015-11-04 CN disclosed