Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975865 | 0.88 | TAAR1 (0.46) | HRH3LMNALTA4HKDM4EMAPT | |
| SCHEMBL28036394 | 0.85 | ALOX5 (0.39) | SMN1; SMN2LMNAKDM4EMAPTXBP1 | |
| SCHEMBL28036416 | 0.83 | PTGS2 (0.47) | SMN1; SMN2LMNAKDM4EMAPTXBP1 | |
| SCHEMBL28822843 | 0.82 | HTR7 (0.35) | HRH3LTA4HNEK1NOS3NOS1 | |
| SCHEMBL27975845 | 0.82 | LOXL2 (0.51) | SMN1; SMN2LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL28036417 | 0.79 | ACHE (0.46) | SMN1; SMN2LMNAMAPTMAPK1NPSR1 | |
| SCHEMBL27975859 | 0.75 | ALDH1A1 (0.37) | SMN1; SMN2LMNAKDM4EMAPTCYP2C9 | |
| SCHEMBL28036701 | 0.74 | SIRT1 (0.40) | LMNAKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL27975546 | 0.70 | ALDH1A1 (0.40) | SMN1; SMN2LMNAKDM4EMAPTMAPK1 | |
| SCHEMBL27975579 | 0.70 | TP53 (0.43) | MAPTMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980248-B | 3,5-bis-substituted-4-amino thiophene-2-formaldehyde compound and preparation method thereof | ZHEJIANG UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |