Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975542 | 0.77 | ERN1 (0.41) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL6768967 | 0.70 | ADORA2A (0.44) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL9696347 | 0.68 | PRKDC (0.41) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL18631516 | 0.67 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL7007247 | 0.67 | POLB (0.39) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL27728844 | 0.65 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL11844529 | 0.64 | PRKDC (0.39) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL28036701 | 0.64 | SIRT1 (0.40) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL7807404 | 0.64 | ADORA2A (0.48) | MEN1KMT2AALDH1A1HSD17B10ALOX15 | |
| SCHEMBL19199419 | 0.63 | ADORA2A (0.49) | MEN1KMT2AALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980248-B | 3,5-bis-substituted-4-amino thiophene-2-formaldehyde compound and preparation method thereof | ZHEJIANG UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |