Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16818904 | 0.80 | ALDH3A1 (0.50) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL29526316 | 0.80 | ALDH3A1 (0.50) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL16818821 | 0.79 | CCR2 (0.52) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL16254657 | 0.79 | NOD1 (0.46) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL7214149 | 0.76 | NOD2 (0.62) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL16818895 | 0.76 | NOD1 (0.43) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL21064305 | 0.76 | PPARG (0.47) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL16818540 | 0.76 | NOD1 (0.47) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL3528148 | 0.76 | PPARG (0.48) | ALDH3A1HPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL7213488 | 0.76 | PPARG (0.48) | ALDH3A1HPGDALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-A | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-09 | — | — | CN | disclosed |