Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529999 | 0.87 | KAT2B (0.38) | ALDH1A1HTTMAPTALOX12KCNH2 | |
| SCHEMBL27380663 | 0.83 | ALOX5 (0.44) | ADRB1NOTUM | |
| SCHEMBL27743313 | 0.82 | ALOX5 (0.48) | ADRB1NOTUMSLC6A4LMNAALDH1A1 | |
| SCHEMBL27873898 | 0.76 | NOTUM (0.36) | NOTUMLMNAALDH1A1HTTMAPT | |
| SCHEMBL28103270 | 0.76 | ALDH1A1 (0.34) | SLC6A2SLC6A4LMNAALDH1A1 | |
| SCHEMBL27671224 | 0.76 | ALOX5 (0.41) | ADRB1NOTUMALOX12L3MBTL1 | |
| SCHEMBL27873897 | 0.75 | ALOX5 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL28103276 | 0.74 | KDM4E (0.39) | KCNH2 | |
| SCHEMBL28158046 | 0.73 | FFAR4 (0.34) | ADRB1HTTSMN1; SMN2 | |
| SCHEMBL28103547 | 0.73 | ADRB2 (0.41) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061322-A | Preparation method of N-substituted 3-hydroxypyrazole compound | BEIJING NUTRICHEM CO LTD | 2015-11-18 | — | — | CN | disclosed |