Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671224 | 0.76 | ALOX5 (0.41) | KMT2AALOX5ADRB1 | |
| SCHEMBL28103547 | 0.73 | ADRB2 (0.41) | NPSR1SMN1; SMN2 | |
| SCHEMBL27873898 | 0.73 | NOTUM (0.36) | NPSR1TSHRHTT | |
| SCHEMBL28103270 | 0.73 | ALDH1A1 (0.34) | TSHR | |
| SCHEMBL27380663 | 0.73 | ALOX5 (0.44) | KMT2AALOX5ADRB1 | |
| SCHEMBL28103613 | 0.73 | MGLL (0.37) | KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28039321 | 0.73 | ADRB1 (0.45) | ADRB1HTTSMN1; SMN2 | |
| SCHEMBL27743313 | 0.73 | ALOX5 (0.48) | KMT2AALOX5ADRB1HTTSMN1; SMN2 | |
| SCHEMBL28103502 | 0.72 | ALOX5 (0.47) | KMT2AALOX5 | |
| SCHEMBL28103276 | 0.71 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021928-A | New intermediate of eltrombopag olamine and its preparation method and application | 常州制药厂有限公司 | 2017-08-08 | — | — | CN | disclosed |