Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040414 | 0.85 | ESR1 (0.38) | LMNATSHRALOX12ACHEESR1 | |
| SCHEMBL28040845 | 0.83 | LMNA (0.32) | LMNATSHRALOX12ACHECDC25A | |
| SCHEMBL28040774 | 0.80 | — | — | |
| SCHEMBL28040447 | 0.73 | ESR1 (0.38) | LMNATSHRESR1ESR2 | |
| SCHEMBL7270394 | 0.70 | — | — | |
| SCHEMBL19264047 | 0.67 | DRD2 (0.43) | LMNATSHRALOX12ACHECDC25A | |
| SCHEMBL28823631 | 0.67 | CDC25A (0.35) | CDC25ACDC25B | |
| SCHEMBL439492 | 0.67 | ESR1 (0.48) | LMNATSHRALOX12ACHEESR1 | |
| SCHEMBL6237048 | 0.67 | LMNA (0.31) | LMNATSHRALOX12ACHEESR1 | |
| SCHEMBL216778 | 0.66 | LMNA (0.38) | LMNATSHRALOX12ACHECDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |