Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040411 | 0.85 | HDAC4 (0.37) | PTPN1MAPTRAB9ANPSR1PDK2 | |
| SCHEMBL28823631 | 0.79 | CDC25A (0.35) | PTPN1 | |
| SCHEMBL28040837 | 0.74 | KDM4E (0.31) | METAP2PTPN1MAPTLMNAMEN1 | |
| SCHEMBL27870094 | 0.69 | MEN1 (0.35) | MAPTRAB9ANPSR1LMNAMEN1 | |
| SCHEMBL28040843 | 0.69 | MAPT (0.39) | MAPTRAB9APDK2LMNAAPAF1 | |
| SCHEMBL28040389 | 0.69 | NPC1 (0.39) | MAPTRAB9ANPSR1MEN1KMT2A | |
| SCHEMBL25693837 | 0.68 | LMNA (0.34) | METAP2NPSR1LMNAKIF11 | |
| SCHEMBL12818300 | 0.67 | METAP2 (0.35) | METAP2LMNAKDM4ESMN1; SMN2KIF11 | |
| SCHEMBL12817489 | 0.67 | METAP2 (0.35) | METAP2LMNAKDM4ESMN1; SMN2KIF11 | |
| SCHEMBL338867 | 0.65 | GABRA1 (0.46) | MAPTLMNAKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |