Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040770 | 0.79 | PTAFR (0.33) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL28040608 | 0.74 | LMNA (0.34) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL28040814 | 0.70 | LOXL2 (0.45) | SMN1; SMN2ALDH1A1KIF11 | |
| SCHEMBL27870094 | 0.69 | MEN1 (0.35) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL28040839 | 0.69 | METAP2 (0.34) | MAPTSMN1; SMN2NPC1LMNAMAPK1 | |
| SCHEMBL28040389 | 0.69 | NPC1 (0.39) | MAPTNPC1ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL12816526 | 0.67 | TP53 (0.44) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL12815746 | 0.67 | TP53 (0.44) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| Ethylbenzene SCHEMBL3663827 | 0.67 | TP53 (0.82) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL12815273 | 0.65 | TP53 (0.43) | MAPTSMN1; SMN2NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |