SCHEMBL28041350

SCHEMBL28041350

CC(C)c1cccc(-c2cccc3c2C=CC3[Hf](C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
RXRA P19793 2/20 0.35
RXRB P28702 1/20 0.35
RXRG P48443 1/20 0.35
NR4A2 P43354 1/20 0.33
PTPN5 P54829 2/20 0.32
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041213 0.86 BRD4 (0.34) BRD4CREBBPL3MBTL1
SCHEMBL27978443 0.81 CHRNB2 (0.33) BRD4
SCHEMBL28041360 0.79 EDNRB (0.32) BRD4CREBBP
SCHEMBL28041345 0.78 KIF11 (0.38) RXRARXRBPTPN5
SCHEMBL28041133 0.77 HTR7 (0.37)
SCHEMBL17415212 0.76 BRD4 (0.35) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415210 0.74 BRD4 (0.36) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415031 0.74 RXRA (0.35) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17387333 0.74 RXRA (0.35) BRD4CREBBPRXRARXRBRXRG
SCHEMBL18124398 0.74 RXRA (0.33) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026408-B Metallocene compound, olefin polymer catalyst, the manufacturing method of olefin polymer and olefin polymer 日本聚乙烯株式会社 2018-09-11 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed