SCHEMBL28042222

SCHEMBL28042222

Cc1cc2c(N)cccc2nc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
KDM4E B2RXH2 3/20 0.56
POLB P06746 2/20 0.56
KMT2A Q03164 2/20 0.56
HPGD P15428 2/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
LMNA P02545 1/20 0.56
GLA P06280 1/20 0.56
GAA P10253 1/20 0.56
PTBP1 P26599 1/20 0.56
RCE1 Q9Y256 1/20 0.56
HSD17B10 Q99714 3/20 0.55
MEN1 O00255 1/20 0.55
TDP2 O95551 1/20 0.55
NSD2 O96028 1/20 0.55
MAPT P10636 1/20 0.55
BLM P54132 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CYP1A2 P05177 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3826117 0.85 NCF1 (0.56) ALDH1A1KDM4EPOLBKMT2AHPGD
SCHEMBL862361 0.82 PDE3B (0.49) ALDH1A1HPGDHSD17B10CYP1A2NUDT1
SCHEMBL19700637 0.77 GPR3 (0.44) ALDH1A1KDM4EHPGDGAAHSD17B10
SCHEMBL7516105 0.77 ALDH1A1 (0.48) ALDH1A1KDM4EKMT2AHPGDRAB9A
SCHEMBL29923623 0.77 BACE1 (0.47) ALDH1A1KDM4EKMT2AHPGDLMNA
SCHEMBL24916325 0.77 BACE1 (0.47) ALDH1A1KDM4EKMT2AHPGDLMNA
SCHEMBL17942715 0.77 PDE3B (0.49) ALDH1A1KDM4EPOLBKMT2AHPGD
SCHEMBL24915591 0.74 DHFR (0.48) ALDH1A1HPGDLMNAHSD17B10BLM
SCHEMBL28492152 0.74 KDM4E (0.47) ALDH1A1KDM4EHPGDGAARCE1
SCHEMBL28961997 0.73 BACE1 (0.47) ALDH1A1KMT2AHPGDHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382969-B Phenylpyrazole zwitterionic compound and application thereof in resistant pest control 华南农业大学 2020-08-07 CN disclosed
CN-107382969-A Phenyl pyrazoles zwitterionic compound and its application in resistant insect preventing and treating 华南农业大学 2017-11-24 CN disclosed
CN-104356006-B Benzylamine, their preparation method and they as anti-inflammatory agent purposes 拜耳知识产权有限责任公司 2017-09-29 CN disclosed
CN-105136787-A Detection reagent for mono-hydroxyphenyl metabolin urine SHANGHAI FEI JI BIOTECHNOLOGY CO LTD 2015-12-09 CN disclosed