Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112916 | 0.83 | KEAP1 (0.51) | ECE2KDM4EKEAP1NFE2L2 | |
| SCHEMBL28045840 | 0.79 | OPRM1 (0.47) | KDM4E | |
| SCHEMBL27782129 | 0.79 | ACHE (0.47) | MCHR1 | |
| SCHEMBL28010202 | 0.78 | MEN1 (0.44) | CCR3ALDH1A1 | |
| SCHEMBL27791259 | 0.78 | CCR3 (0.45) | MCHR1CCR3ALDH1A1 | |
| SCHEMBL27841081 | 0.78 | GABRP (0.40) | — | |
| SCHEMBL27819618 | 0.78 | SLC6A4 (0.38) | CCR3KDM4EALDH1A1MGLL | |
| SCHEMBL28824741 | 0.77 | MCHR1 (0.48) | MCHR1CCR3ALDH1A1 | |
| SCHEMBL28087020 | 0.77 | CCR3 (0.49) | CCR3 | |
| SCHEMBL28045809 | 0.76 | SLC2A1 (0.49) | CCR3KDM4EALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143222-B | Glycosidase inhibitor | 默克专利有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105143222-A | Glycosidase inhibitors | MERCK PATENT GMBH | 2015-12-09 | — | — | CN | disclosed |