Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202187 | 0.88 | SLC2A1 (0.53) | SLC2A1CCR5HIF1AEPAS1CCR3 | |
| SCHEMBL28045840 | 0.85 | OPRM1 (0.47) | CCR5KDM4E | |
| SCHEMBL27846335 | 0.85 | CCR5 (0.51) | CCR5ALDH1A1 | |
| SCHEMBL28010202 | 0.84 | MEN1 (0.44) | CCR3ALDH1A1 | |
| SCHEMBL27791259 | 0.84 | CCR3 (0.45) | CCR5CCR3SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27579513 | 0.82 | CARM1 (0.56) | LPLLIPGMGLLKDM4EALDH1A1 | |
| SCHEMBL28853073 | 0.81 | GAA (0.48) | ALDH1A1 | |
| SCHEMBL16112715 | 0.81 | TGFBR1 (0.54) | SLC2A1CCR5LIPECYP2C9CYP2C19 | |
| SCHEMBL1812750 | 0.81 | SLC2A1 (0.48) | SLC2A1CCR5HIF1AEPAS1CCR3 | |
| SCHEMBL1760952 | 0.81 | LPL (0.49) | SLC2A1CCR5HIF1AEPAS1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143222-B | Glycosidase inhibitor | 默克专利有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105143222-A | Glycosidase inhibitors | MERCK PATENT GMBH | 2015-12-09 | — | — | CN | disclosed |