Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045840 | 0.88 | OPRM1 (0.47) | L3MBTL1LMNA | |
| SCHEMBL27791259 | 0.86 | CCR3 (0.45) | MEN1KMT2ACCR3ALDH1A1L3MBTL1 | |
| SCHEMBL27719507 | 0.85 | SPHK1 (0.40) | ALDH1A1 | |
| SCHEMBL28045809 | 0.84 | SLC2A1 (0.49) | CCR3ALDH1A1 | |
| SCHEMBL27841081 | 0.84 | GABRP (0.40) | — | |
| SCHEMBL27846335 | 0.82 | CCR5 (0.51) | ALDH1A1 | |
| SCHEMBL31029209 | 0.82 | CARM1 (0.40) | — | |
| SCHEMBL4773737 | 0.80 | KDM4E (0.52) | ALDH1A1L3MBTL1HTT | |
| SCHEMBL27782129 | 0.80 | ACHE (0.47) | — | |
| SCHEMBL28024936 | 0.80 | LMNA (0.53) | MEN1KMT2AALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684906-A | NAMPT inhibitors | ABBVIE INC | 2015-06-03 | — | — | CN | disclosed |