SCHEMBL1682004

SCHEMBL1682004

CC(=O)Oc1nccn1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
LPO P22079 1/20 0.39
FDPS P14324 2/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 3/20 0.33
NAMPT P43490 1/20 0.33
POLB P06746 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28386445 0.84 CHRNB2 (0.40) CHRNB2CHRNA4LPOFDPSNPC1
SCHEMBL6673530 0.82 CHRNB2 (0.39) CHRNB2CHRNA4LPOFDPSNPC1
SCHEMBL16991360 0.78 CHRNB2 (0.40) CHRNB2CHRNA4LPOFDPSNPC1
SCHEMBL2285950 0.78 KMT2A (0.39) CHRNB2CHRNA4LPOFDPSNPC1
SCHEMBL28324902 0.78 CHRNB2 (0.36) CHRNB2CHRNA4LPOFDPSNPC1
SCHEMBL1681999 0.76 SMN1; SMN2 (0.37) LPOSMN1; SMN2KMT2APOLBALDH1A1
SCHEMBL2804720 0.75 KMT2A (0.52) SMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL26112999 0.74 ELANE (0.39) CHRNB2CHRNA4MAPT
SCHEMBL9499479 0.73 TSHR (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1TP53
SCHEMBL2488201 0.73 ALDH1A1 (0.39) NPC1RAB9ASMN1; SMN2KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120022522-A Drug-loaded microneedle, drug-loaded microneedle patch and electrically-controlled drug release microneedle system 成都邦迈医创科技有限公司 2025-05-23 CN claimed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN claimed
US-12272495-B2 Systems and methods for improved supercapacitors with ionic liquid electrolytes THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-04-08 US claimed
WO-2023240046-A2 MULTI-OMICS ASSESSMENT PrognomIQ, Inc. (US) 2023-12-14 WO claimed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN claimed
US-20200321165-A1 Systems And Methods For Improved Supercapacitors With Ionic Liquid Electrolytes INMATECH INC. 2020-10-08 US claimed
CN-106537145-B Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment 麦特博隆股份有限公司 2020-08-25 CN claimed
CN-108276567-B Application of ionic liquid as catalyst in preparation of liquid crystal polyester and preparation method of liquid crystal polyester 金发科技股份有限公司 2020-07-14 CN claimed
CN-110982339-A Graphene-based flexible sensor prepared by 3D printing, preparation method and application 郑州中科新兴产业技术研究院 2020-04-10 CN claimed
CN-110344236-A A kind of tea grounds modified function quilted stockings of antibacterial and deodouring and preparation method thereof 安徽农业大学 2019-10-18 CN claimed
CN-110272551-A A kind of polylactic acid film and preparation method thereof 梁真 2019-09-24 CN claimed
CN-109293959-A Tea grounds modified oxidized cellulose composite membrane and the preparation method and application thereof 安徽农业大学 2019-02-01 CN claimed
CN-109295719-A A kind of chitin modified oxidized fibre cellulose fabric of durable antibiotic and preparation method thereof 安徽农业大学 2019-02-01 CN claimed
US-20100273207-A1 Methods for Diagnosis of Sepsis and Risk of Death LANGLEY RAYMOND 2010-10-28 US claimed
WO-2010124269-A1 METHODS FOR DIAGNOSIS OF SEPSIS AND RISK OF DEATH NATIONAL CENTER FOR GENOME RESOURCES (US) 2010-10-28 WO claimed
US-6361940-B1 IMMOBILIZATION; GENETIC ENGINEERING QIAGEN GENOMICS, INC. 2002-03-26 US claimed
US-4333884-A Production of acetic anhydride HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US claimed
US-4319038-A BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-09 US claimed
US-20260031230-A1 METHODS OF IDENTIFYING PANCREATIC CANCER PROGNOMIQ INC (US) 2026-01-29 US disclosed
US-20250388973-A1 MULTI-OMICS ASSESSMENT PROGNOMIQ INC (US) 2025-12-25 US disclosed
EP-4249535-B1 LIQUID CRYSTAL POLYESTER, (LCP), LCP COMPOSITION, AND USE THEREOF KINGFA SCIENCE & TECHNOLOGY CO (CN) 2025-11-05 EP disclosed
US-20250242275-A1 APPARATUS AND METHOD FOR PROCESSING A BIOMASS MATERIAL BUSS-SMS-CANZLER GMBH (DE) 2025-07-31 US disclosed
US-20250205925-A1 ENGINEERED STRUCTURES FABRICATED FROM SCRAP MATERIALS, AND SYSTEMS AND METHODS FOR FABRICATION AND USE THEREOF UNIVERSITY OF MARYLAND, COLLEGE PARK 2025-06-26 US disclosed
CN-120022522-A Drug-loaded microneedle, drug-loaded microneedle patch and electrically-controlled drug release microneedle system 成都邦迈医创科技有限公司 2025-05-23 CN disclosed
US-20250145889-A1 METHOD FOR PROCESSING A BIOMASS MATERIAL PROIONIC GMBH (AT) 2025-05-08 US disclosed
CN-119816897-A Multiple study assessment 普罗科技有限公司 2025-04-11 CN disclosed
US-12272495-B2 Systems and methods for improved supercapacitors with ionic liquid electrolytes THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-04-08 US disclosed
CN-111868260-B Methods and materials for assessing and treating cancer 约翰斯霍普金斯大学 2025-02-21 CN disclosed
CN-119264808-A Composition, ionic gel coating, preparation method and application thereof 清华大学 2025-01-07 CN disclosed
CN-116102723-B Liquid crystal polyester, preparation method thereof and liquid crystal polyester composition 珠海万通特种工程塑料有限公司 2024-08-27 CN disclosed
US-20240219399-A1 DIFFERENTIAL DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2024-07-04 US disclosed
EP-4377467-A2 METHOD FOR PROCESSING A BIOMASS MATERIAL proionic GmbH (AT) 2024-06-05 EP disclosed
EP-4103946-B1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2024-03-13 EP disclosed
WO-2023240046-A2 MULTI-OMICS ASSESSMENT PrognomIQ, Inc. (US) 2023-12-14 WO disclosed
US-20230391950-A1 LIQUID CRYSTAL POLYESTER (LCP), LCP COMPOSITION, AND USE THEREOF KINGFA SCI. & TECH. CO., LTD. (CN) 2023-12-07 US disclosed
EP-4249535-A1 LIQUID CRYSTAL POLYESTER, LIQUID CRYSTAL POLYESTER COMPOSITION, AND USE THEREOF KINGFA SCI. & TECH. CO., LTD. (CN) 2023-09-27 EP disclosed
CN-112662006-B Antibacterial waterproof breathable film and preparation method thereof 深圳技术大学 2023-05-23 CN disclosed
WO-2023084131-A2 METHOD FOR PROCESSING A BIOMASS MATERIAL PROIONIC GMBH (AT) 2023-05-19 WO disclosed
CN-116102723-A Liquid crystal polyester, preparation method thereof and liquid crystal polyester composition 珠海万通特种工程塑料有限公司 2023-05-12 CN disclosed
CN-115975261-A Cellulose-based microsphere based on metal salt and preparation method and application thereof 中国科学院化学研究所 2023-04-18 CN disclosed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
US-20230109016-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2023-04-06 US disclosed
WO-2023017050-A1 DIFFERENTIAL DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2023-02-16 WO disclosed
EP-4134672-A1 DIFFERENTIAL DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME Immundiagnostik AG (DE) 2023-02-15 EP disclosed
EP-4103946-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME Immundiagnostik AG (DE) 2022-12-21 EP disclosed
CN-115448908-A Compounds for the treatment of specific leukemias 拓臻股份有限公司 2022-12-09 CN disclosed
CN-112250846-B Liquid crystal polyester, liquid crystal polyester composition and application 金发科技股份有限公司 2022-12-02 CN disclosed
CN-115215838-A Compounds for the treatment of specific leukemias 拓臻股份有限公司 2022-10-21 CN disclosed
CN-111041610-B Melamine/cellulose flame-retardant material and preparation method thereof 郑州中科新兴产业技术研究院 2022-09-09 CN disclosed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP disclosed
CN-110330459-B Carboxylate ionic liquid and preparation method and application thereof 中国科学院过程工程研究所 2022-07-08 CN disclosed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN disclosed
US-20220161195-A1 IONIC LIQUID-CONTAINING STRUCTURE NITTO DENKO CORPORATION (JP) 2022-05-26 US disclosed
WO-2022088565-A1 LIQUID CRYSTAL POLYESTER, LIQUID CRYSTAL POLYESTER COMPOSITION, AND USE THEREOF 金发科技股份有限公司 2022-05-05 WO disclosed
EP-3943180-A1 STRUCTURE CONTAINING IONIC LIQUID NITTO DENKO CORPORATION (JP) 2022-01-26 EP disclosed
CN-113597337-A Structure containing ionic liquid 日东电工株式会社 2021-11-02 CN disclosed
CN-110344236-B Antibacterial and deodorant tea residue modified functional cotton sock and preparation method thereof 安徽农业大学 2021-08-20 CN disclosed
WO-2021160696-A1 IN-VITRO DIAGNOSIS OF HISTAMINE INTOLERANCE SYNDROME IMMUNDIAGNOSTIK AG (DE) 2021-08-19 WO disclosed
US-11085124-B2 Electrochemical reaction device KABUSHIKI KAISHA TOSHIBA (JP) 2021-08-10 US disclosed
CN-112662006-A Antibacterial waterproof breathable film and preparation method thereof 深圳技术大学 2021-04-16 CN disclosed
CN-112250846-A Liquid crystal polyester, liquid crystal polyester composition and application 金发科技股份有限公司 2021-01-22 CN disclosed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP disclosed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US disclosed
US-20200377956-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER THE JOHNS HOPKINS UNIVERSITY 2020-12-03 US disclosed
CN-111868260-A Methods and materials for assessing and treating cancer 约翰斯霍普金斯大学 2020-10-30 CN disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
US-20200321165-A1 Systems And Methods For Improved Supercapacitors With Ionic Liquid Electrolytes INMATECH INC. 2020-10-08 US disclosed
CN-106537145-B Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment 麦特博隆股份有限公司 2020-08-25 CN disclosed
CN-108276567-B Application of ionic liquid as catalyst in preparation of liquid crystal polyester and preparation method of liquid crystal polyester 金发科技股份有限公司 2020-07-14 CN disclosed
EP-3665308-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER The Johns Hopkins University (US) 2020-06-17 EP disclosed
CN-111041610-A Melamine/cellulose flame-retardant material and preparation method thereof 郑州中科新兴产业技术研究院 2020-04-21 CN disclosed
CN-110982339-A Graphene-based flexible sensor prepared by 3D printing, preparation method and application 郑州中科新兴产业技术研究院 2020-04-10 CN disclosed
WO-2020022503-A1 NON-COVALENT NANOCARBON-POLYMER HYBRID COMPOSITION 国立大学法人名古屋大学 2020-01-30 WO disclosed
CN-110344236-A A kind of tea grounds modified function quilted stockings of antibacterial and deodouring and preparation method thereof 安徽农业大学 2019-10-18 CN disclosed
CN-110330459-A A kind of carboxylate ion liquid and the preparation method and application thereof 中国科学院过程工程研究所 2019-10-15 CN disclosed
CN-110272551-A A kind of polylactic acid film and preparation method thereof 梁真 2019-09-24 CN disclosed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO disclosed
US-20190256924-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER THE JOHNS HOPKINS UNIVERSITY 2019-08-22 US disclosed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
WO-2019067092-A1 METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2019-04-04 WO disclosed
CN-109293959-A Tea grounds modified oxidized cellulose composite membrane and the preparation method and application thereof 安徽农业大学 2019-02-01 CN disclosed
US-20130031931-A1 ABSORPTION HEAT PUMP WITH SORBENT COMPRISING A LITHIUM SALT AND AN ORGANIC SALT WITH THE SAME ANION EVONIK DEGUSSA GMBH (DE) 2013-02-07 US disclosed
EP-2147947-B1 Process for preparing an aromatic polyether sulfone blockcopolymer UBE INDUSTRIES (JP) 2012-07-25 EP disclosed
US-7923492-B2 Polymer electrolyte composition UBE INDUSTRIES, LTD. (JP) 2011-04-12 US disclosed
EP-2058889-B1 Polymer electrolyte composition UBE INDUSTRIES (JP) 2010-12-01 EP disclosed
US-20100273207-A1 Methods for Diagnosis of Sepsis and Risk of Death LANGLEY RAYMOND 2010-10-28 US disclosed
WO-2010124269-A1 METHODS FOR DIAGNOSIS OF SEPSIS AND RISK OF DEATH NATIONAL CENTER FOR GENOME RESOURCES (US) 2010-10-28 WO disclosed
US-7767852-B2 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2010-08-03 US disclosed
EP-1449886-B1 POLYELECTROLYTE COMPOSITIONS UBE INDUSTRIES (JP) 2010-05-05 EP disclosed
EP-2147947-A1 Process for preparing an aromatic polyether sulfone blockcopolymer Ube Industries, Ltd. (JP) 2010-01-27 EP disclosed
US-20090212253-A1 POLYMER ELECTROLYTE COMPOSITION UBE INDUSTRIES, LTD. (JP) 2009-08-27 US disclosed
US-7563850-B2 Aromatic polymer with either carbonyl and/or sulfone groups and cationic group for conductivity and anhydrous or solvent UBE INDUSTRIES, LTD. (JP) 2009-07-21 US disclosed
US-7544445-B2 Polyelectrolyte membrane and production method therefor UBE INDUSTRIES, LTD. (JP) 2009-06-09 US disclosed
EP-2058889-A1 Polymer electrolyte composition Ube Industries, Ltd. (JP) 2009-05-13 EP disclosed
US-20080214658-A1 Composition Comprising Isoorientin for Suppressing Histamine UNIGEN, INC. (KR) 2008-09-04 US disclosed
EP-1515346-B1 POLYELECTROLYTE MEMBRANE AND PRODUCTION METHOD THEREFOR UBE INDUSTRIES (JP) 2008-09-03 EP disclosed
US-20080083606-A1 preparing aminodihalophosphines, diaminohalophosphines, triaminophosphines, phosphorous ester diamides, aminophosphines, diaminophosphines, phosphorous ester amide halides and aminophosphine halides with elimination of an acid in the presence of an auxiliary base BASF AKTIENGESELLSCHAFT (DE) 2008-04-10 US disclosed
US-7351339-B2 Using an auxiliary base to form a salt with the acid which is liquid at low enough temperature so that value product does not decompose during the removal of the liquid salt; e.g. acid catalyst removal; ionic liquids BASF AKTIENGESELLSCHAFT (DE) 2008-04-01 US disclosed
US-20050221193-A1 Polyelectrolyte membrane and production method therefor UBE INDUSTRIES LTD. (JP) 2005-10-06 US disclosed
US-20050069780-A1 Aromatic polymer with either carbonyl and/or sulfone groups and cationic group for conductivity and anhydrous or solvent UBE INDUSTRIES, LTD (JP) 2005-03-31 US disclosed
EP-1515346-A1 POLYELECTROLYTE MEMBRANE AND PRODUCTION METHOD THEREFOR Ube Industries, Ltd. (JP) 2005-03-16 EP disclosed
US-20050020857-A1 Removal by salt formation BASF AKTIENGESELLSCHAFT (DE) 2005-01-27 US disclosed
EP-1449886-A1 POLYELECTROLYTE COMPOSITIONS Ube Industries, Ltd. (JP) 2004-08-25 EP disclosed
US-6361940-B1 IMMOBILIZATION; GENETIC ENGINEERING QIAGEN GENOMICS, INC. 2002-03-26 US disclosed
EP-0958378-A2 COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY Rapigene, Inc. (US) 1999-11-24 EP disclosed
EP-0952228-A2 Compositions and methods for enhancing hybridization specificity Rapigene, Inc. (US) 1999-10-27 EP disclosed
WO-1998013527-A2 COMPOSITIONS AND METHODS FOR ENHANCING HYBRIDIZATION SPECIFICITY RAPIGENE, INC. (US) 1998-04-02 WO disclosed
EP-0479463-B1 Process for the production of carboxylic acid anhydrides BP CHEM INT LTD (GB) 1995-12-13 EP disclosed
US-5298586-A Reacting carbon monoxide with carboxylic acid, ester or alkyl ether in presence of rhodium catalyst and iodide promoter BP CHEMICALS LIMITED (GB) 1994-03-29 US disclosed
EP-0479463-A2 Process for the production of carboxylic acid anhydrides BP Chemicals Limited (GB) 1992-04-08 EP disclosed
US-4430273-A Production of acetic anhydride HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed
US-4351972-A Process for making anhydrous alkyl iodides HOECHST AKTIENGESELLSCHAFT (DE) 1982-09-28 US disclosed
US-4333884-A Production of acetic anhydride HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4319038-A BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4319038-A BY REACTING METHYL ACETATE OR DIMETHYL ETHER WITH CARBON MONOXIDE AND HYDROGEN IN THE PRESENCE OF A CATALYST SYSTEM WHICH INCLUDES AN ALIPHATIC CARBOXYLIC ACID, A MANGANESE OR RHEMIUM COMPOUND, AND A HETEROCYCLIC NITROGEN-CONTAINING SALT HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388973-A1 MULTI-OMICS ASSESSMENT S100A4, APOL1, SAAL1 CHRNB2 2158/4885CHRNA4 2151/4885LPO 2346/4885
US-20260031230-A1 METHODS OF IDENTIFYING PANCREATIC CANCER FABP2, FABP3, FABP1 CHRNB2 860/4885CHRNA4 589/4885LPO 3798/4885
US-20050020857-A1 Removal by salt formation PHOSPHO1, AASDHPPT, INPP5B CHRNB2 4390/4885CHRNA4 4528/4885LPO 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.