Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047475 | 0.92 | ALDH1A1 (0.63) | LMNAMAPK1GAAALDH1A1MAPT | |
| SCHEMBL1488032 | 0.88 | ALDH1A1 (0.68) | LMNAMAPK1GAAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1530551 | 0.86 | ALDH1A1 (0.65) | LMNAMAPK1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8338495 | 0.85 | KMT2A (0.78) | GAAALDH1A1MAPTCA12CA1 | |
| SCHEMBL27787880 | 0.83 | HTR6 (0.77) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL27875519 | 0.83 | ITGA1 (0.58) | LMNAMAPK1GAAALDH1A1MAPT | |
| SCHEMBL27516685 | 0.83 | CA1 (0.71) | LMNAMAPK1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL21254711 | 0.82 | KIF11 (0.68) | LMNAALDH1A1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL14414968 | 0.80 | LMNA (0.61) | LMNAMAPK1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27787716 | 0.79 | CYP2C9 (0.51) | LMNAMAPK1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746239-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBVIE INC. (BS) | 2016-02-10 | — | — | CN | disclosed |