Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CES1 | P23141 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | CA2 | P00918 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.56 |
| ▸ | IL1RN | P18510 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047457 | 0.92 | LMNA (0.67) | ALDH1A1MEN1KMT2ACES1PKM | |
| SCHEMBL8338495 | 0.92 | KMT2A (0.78) | ALDH1A1MEN1KMT2APKMCA1 | |
| SCHEMBL27875519 | 0.90 | ITGA1 (0.58) | ALDH1A1MEN1KMT2ACES1PKM | |
| SCHEMBL27787880 | 0.90 | HTR6 (0.77) | ALDH1A1MEN1KMT2AHTR6CA1 | |
| SCHEMBL27787716 | 0.86 | CYP2C9 (0.51) | ALDH1A1MEN1KMT2ACES1PKM | |
| SCHEMBL21098626 | 0.84 | UCHL1 (0.59) | ALDH1A1MEN1KMT2ACES1PKM | |
| SCHEMBL13110661 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1MEN1KMT2APKMHTR6 | |
| SCHEMBL2005010 | 0.82 | CA12 (0.81) | ALDH1A1MEN1KMT2APKMCA1 | |
| SCHEMBL27989950 | 0.82 | HTR6 (0.61) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL17593260 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746239-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBVIE INC. (BS) | 2016-02-10 | — | — | CN | disclosed |