Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11363136 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL11363133 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL637319 | 0.75 | RAB9A (0.52) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL29754142 | 0.75 | RAB9A (0.52) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL6653866 | 0.75 | CYP2D6 (0.50) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL7005196 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL11725090 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL31141504 | 0.72 | CYP2D6 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL6162141 | 0.72 | CYP2D6 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL31130749 | 0.72 | CYP2D6 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112535277-A | Oligosaccharide composition used as food ingredient and its preparation method | 卡德纳生物股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-112515178-A | Oligosaccharide composition for nutritional composition and method for producing the same | 卡德纳生物股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105209510-A | Polymeric ionic salt catalysts and methods of producing thereof | MIDORI USA INC | 2015-12-30 | — | — | CN | disclosed |