Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138492 | 0.75 | NOS1 (0.41) | SIGMAR1HRH3 | |
| SCHEMBL28623484 | 0.75 | HPGD (0.40) | HSD11B1LMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28047476 | 0.73 | BRD4 (0.40) | SIGMAR1KMT2AALDH1A1MEN1HPGD | |
| SCHEMBL28252209 | 0.69 | L3MBTL1 (0.38) | SIGMAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL22174750 | 0.65 | — | — | |
| SCHEMBL6263981 | 0.64 | TSHR (0.57) | SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL11139943 | 0.62 | CYP1A2 (0.43) | SIGMAR1ALDH1A1HRH3 | |
| Diphenylmethane SCHEMBL28085719 | 0.61 | CALM1 (0.80) | LMNASIGMAR1HRH3 | |
| Diphenylmethane SCHEMBL28072604 | 0.61 | CALM1 (0.80) | LMNASIGMAR1HRH3 | |
| SCHEMBL9868061 | 0.61 | SIGMAR1 (0.73) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822037-A | A kind of method of efficient high atom economy synthesis imidazolidine derivatives | 复旦大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-105218451-A | A kind of method of narrowing of rare earth catalyst ring Reactive Synthesis imidazolidine derivatives | UNIV FUDAN | 2016-01-06 | — | — | CN | disclosed |