Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047544 | 0.75 | HSD11B1 (0.42) | HPGDHSD11B1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL28617084 | 0.73 | BRD4 (0.37) | HPGDHSD11B1ALDH1A1 | |
| SCHEMBL5012240 | 0.69 | HSD11B1 (0.41) | HPGDHSD11B1GAAALOX15ALDH1A1 | |
| SCHEMBL17083743 | 0.67 | SLC18A3 (0.39) | HPGDHSD11B1SLC18A3GAAALDH1A1 | |
| SCHEMBL28628545 | 0.65 | OPRD1 (0.39) | HPGDALDH1A1KDM4ELMNA | |
| Biphenyl SCHEMBL27783355 | 0.63 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL13728374 | 0.63 | NPC1 (0.37) | HPGDSMN1; SMN2ABL1EGFRSRC | |
| SCHEMBL5014179 | 0.62 | LMNA (0.49) | GAAALDH1A1CES2KDM4ELMNA | |
| SCHEMBL8250269 | 0.61 | SLC18A3 (0.43) | HPGDHSD11B1SLC18A3ALDH1A1ABL1 | |
| Biphenyl SCHEMBL28005894 | 0.61 | ALDH1A1 (0.47) | HPGDGAAALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822037-B | Method for efficiently synthesizing imidazoline derivative with high atom economy | 复旦大学 | 2021-08-20 | — | — | CN | claimed |
| CN-108822037-B | Method for efficiently synthesizing imidazoline derivative with high atom economy | 复旦大学 | 2021-08-20 | — | — | CN | disclosed |