Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949763 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL9586577 | 0.79 | KDM4E (0.51) | ALDH1A1LMNAGABRA2SMN1; SMN2HPGDS | |
| SCHEMBL948199 | 0.79 | KDM4E (0.50) | ALDH1A1LMNASMN1; SMN2HTTTDP1 | |
| SCHEMBL27849366 | 0.78 | NR4A2 (0.42) | ALDH1A1LMNASMN1; SMN2HTTHSD17B10 | |
| SCHEMBL30731570 | 0.76 | ALDH1A1 (0.48) | ALDH1A1LMNAGRM6GABRA1GABRG2 | |
| SCHEMBL954343 | 0.76 | BCAT2 (0.47) | ALDH1A1LMNASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL38655809 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL7421480 | 0.74 | ALDH1A1 (0.41) | ALDH1A1LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL7402340 | 0.74 | LMNA (0.70) | ALDH1A1LMNAGRM6GABRA1GABRG2 | |
| SCHEMBL28778787 | 0.73 | KMT2A (0.44) | ALDH1A1LMNAGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377851-A | BET bromodomain inhibitors and therapeutic methods using these inhibitors | UNIV MICHIGAN REGENTS | 2016-03-02 | — | — | CN | disclosed |