Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.55 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.55 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23906392 | 0.87 | HTT (0.60) | HTTHSD17B10SMN1; SMN2KMT2APDK1 | |
| SCHEMBL4572080 | 0.83 | PDK1 (0.74) | HTTL3MBTL1SMN1; SMN2KMT2APDK1 | |
| SCHEMBL28208041 | 0.81 | HTT (0.65) | HTTHSD17B10SMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL12480670 | 0.81 | L3MBTL1 (0.61) | HTTL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL10264545 | 0.81 | SMN1; SMN2 (0.67) | HTTHSD17B10SMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL28738749 | 0.81 | LMNA (0.65) | HTTL3MBTL1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL4113495 | 0.81 | EPHX2 (0.62) | HTTL3MBTL1SMN1; SMN2KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL20570274 | 0.80 | HTT (0.48) | HTTHSD17B10L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL6616170 | 0.80 | ALDH1A1 (0.66) | HTTHSD17B10SMN1; SMN2KMT2ANR1H4 | |
| SCHEMBL1142037 | 0.80 | HTT (0.72) | HTTHSD17B10L3MBTL1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105348048-A | Method for preparing aryl trifluoroethoxyl ether | NAT UNIV DONG HWA | 2016-02-24 | — | — | CN | disclosed |