Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.74 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.74 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.74 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571973 | 0.85 | PDK1 (0.67) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL12480670 | 0.85 | L3MBTL1 (0.61) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL306383 | 0.85 | PDK1 (0.71) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL27760702 | 0.84 | PDK1 (0.74) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL2888920 | 0.83 | CASR (0.61) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL28048892 | 0.83 | HTT (0.59) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL144943 | 0.83 | CYP1A2 (0.58) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL5112533 | 0.83 | L3MBTL1 (0.58) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL8285861 | 0.83 | PDK1 (0.68) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL20981664 | 0.82 | L3MBTL1 (0.82) | PDK1PDK2PDK3PDK4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102206172-B | Substituted diaryl compound and preparation method and antiviral application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-02-25 | — | — | CN | claimed |
| CN-102206172-A | Substituted diaryl compound and preparation method and antiviral application thereof | INST MED BIOTECHNOLOGY CAMS | 2011-10-05 | — | — | CN | claimed |
| CN-114507867-B | Preparation method of fluoroamide derivative | 哈尔滨工业大学（深圳） | 2023-04-14 | — | — | CN | disclosed |
| CN-114507867-A | Preparation method of fluoroamide derivative | 哈尔滨工业大学（深圳） | 2022-05-17 | — | — | CN | disclosed |
| US-10189777-B2 | Benzenesulfonamido and related compounds for use as agonists of RORγ and the treatment of disease | LYCERA CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
| EP-3209641-A2 | BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF ROR AND THE TREATEMENT OF DISEASE | Lycera Corporation (US) | 2017-08-30 | — | — | EP | disclosed |
| US-20170190659-A1 | BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2017-07-06 | — | — | US | disclosed |
| CN-102869647-B | As 5-HT6Sulfone compounds of receptor ligands | SUVEN LIFE SCIENCES LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-102206172-B | Substituted diaryl compound and preparation method and antiviral application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-02-25 | — | — | CN | disclosed |
| EP-2445969-B1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2014-08-27 | — | — | EP | disclosed |
| US-8735444-B2 | Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-05-27 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1671945-A1 | PROCESS FOR PRODUCTION OF 1-ARYL-5-(TRIFLUOROMETHYL)-1H- TETRAZOLES | Toyo Kasei Kogyo Company Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-5475106-A | Agonist for cholecystokinin and gastrin receptors; nervous system, gastrointestinal disorders | RHONE-POULENC RORER S.A. (FR) | 1995-12-12 | — | — | US | disclosed |
| EP-0572455-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | Astra Pharmaceuticals Limited (GB) | 1993-12-08 | — | — | EP | disclosed |
| WO-1992014714-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | FISONS PLC (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |
| EP-0049555-B1 | 2-TRIFLUOROMETHYL-4-HYDROXY-3 QUINOLINE-CARBOXYLIC-ACID DERIVATIVES AND THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1984-02-22 | — | — | EP | disclosed |
| US-4299831-A | 2-Trifluoromethyl-3-quinoline carboxamides, analgesic and anti-inflammatory compositions and methods employing them | ROUSSEL UCLAF (FR) | 1981-11-10 | — | — | US | disclosed |
| EP-0012639-A2 | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189777-B2 | Benzenesulfonamido and related compounds for use as agonists of RORγ and the treatment of disease | RORC, RORB, RORA | PDK1 2626/4885PDK2 1959/4885PDK3 1888/4885 |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TH, NAT1, PAH | PDK1 3510/4885PDK2 1327/4885PDK3 2948/4885 |
| US-20170190659-A1 | BENZENESULFONAMIDO AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE | RORB, RORA, RORC | PDK1 2951/4885PDK2 1689/4885PDK3 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.