SCHEMBL28049491

SCHEMBL28049491

O=S(=O)(c1ccc(S)cc1)c1ccccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.46
HSD11B1 P28845 1/20 0.46
AKR1B1 P15121 1/20 0.45
NAMPT P43490 2/20 0.45
MMP1 P03956 5/20 0.44
MMP2 P08253 5/20 0.44
MMP9 P14780 5/20 0.44
MMP8 P22894 5/20 0.44
MMP12 P39900 5/20 0.44
MMP13 P45452 5/20 0.44
MMP14 P50281 5/20 0.44
MMP16 P51512 5/20 0.44
MMP3 P08254 4/20 0.44
HTR6 P50406 6/20 0.43
KMT2A Q03164 1/20 0.42
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
CASP1 P29466 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9242466 0.87 HTR6 (0.55) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL8844836 0.83 HTR6 (0.55) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL20379701 0.82 HTR6 (0.56) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL3297607 0.82 HSD11B1 (0.63) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL5161585 0.82 PTGS2 (0.54) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL28175716 0.82 LMNA (0.55) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL4539686 0.81 HSD11B1 (0.45) PTGS2HSD11B1AKR1B1NAMPTMMP1
SCHEMBL31463127 0.80 AKR1B1 (0.56) PTGS2HSD11B1AKR1B1NAMPTHTR6
SCHEMBL9599324 0.80 HTR6 (0.42) PTGS2HSD11B1MMP1MMP2MMP9
SCHEMBL27844440 0.79 HTR6 (0.54) PTGS2MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385084-A Polarizing plate, composition for protective layer of polarizing plate, and optical display SAMSUNG SDI CO LTD 2016-03-09 CN disclosed